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Aniston starred in the comedy movie Horrible Bosses (2011), with Colin Farrell, Jason Bateman, Charlie Day, and Jamie Foxx, directed by Seth Gordon.
The film focuses on a trio of employees who plot to murder their titular tyrannical supervisors.
She gained critical acclaim for her performance in the low-budget film The Good Girl (2002), playing an unglamorous cashier who cheats on her husband.
The latter film opened in relatively few theaters – under 700 in total – taking In 2002, film critic Roger Ebert declared the role as her breakthrough film, stating that, "after languishing in a series of overlooked movies that ranged from the entertaining Office Space to the disposable Picture Perfect (1997), Jennifer Aniston has at last decisively broken with her "Friends" image in an independent film of satiric fire and emotional turmoil. Club wrote, "Aniston plays Jules' therapist, and the part is more or less a twist on the old, 'The psychiatrist is crazier than the patient!
In 2008, she co-founded the production company Echo Films.
In 2012, Aniston received a star on the Hollywood Walk of Fame.
Aniston played one of the bosses, a sexually aggressive dentist who harasses Charlie Day's character.
In 2015, she played Jane Claremont in She's Funny That Way directed by Peter Bogdanovich.The character was widely popular during the airing of the series and was later recognized as one of the 100 greatest female characters in United States television.Aniston has played the female protagonist in a number of comedies and romantic comedies.The head of NBC entertainment encouraged Aniston to continue acting, and a few months later helped cast her for Friends, but Courteney Cox was considered to be better suited to the role. She was also offered a spot as a featured player on Saturday Night Live, but turned it down to do Friends.1 million per episode for the last two seasons of Friends, as well as five Emmy nominations (two for Supporting Actress, three for Lead Actress), including a win for Outstanding Lead Actress in a Comedy Series.She was also nominated for two Golden Globe Awards and won, in 2003, the Golden Globe Award for Best Actress – Television Series Musical or Comedy.